PROSPERous: an integrative tool for predicting substrate cleavage sites of various proteases

PROSPERous is an integrative server for in silico prediction of protease-specific substrates and their cleavage sites from amino acid sequences. PROPSERous is primarily based on amino acid weights derived from amino acid occurrences, through a combination of multiple scoring functions to score, predict and rank potential cleavage sites of proteases. Therefore, PROSPERous is a powerful tool for substrate identification in protease systems biology that complements the existing prediction tools such as PoPS 1.0 and PROSPER.

BASIC PARAMETERS

Input sequence (s) (example): [?]

Select protease: [?]

ADVANCED PARAMETERS

Select cleavage site P4-Pn': [?]

Select scoring function: [?]

Select top ranking results: [?]

If you find PROSPERous is useful in your research, please cite:

PROSPERous: a comprehensive server for predicting protease-specific substrates and cleavage sites using a combination of multiple scoring functions. Bioinformatics, Volume 34, Issue 4, 15 February 2018, Pages 684-687.